There is an urgent need to identify patients, before treatment begins, who are likely to respond positively to physical therapy. In collaboration with Shawn Roll, Ph.D., OTR/L, CWCE, we are combining sonography and electromyography (EMG) to obtain objective measures to enhance clinical screening to better identify CP/CPPS patients appropriate for physical therapy. We aim to identify a set of neuromuscular biomarkers for CP/CPPS patients using sonographic imaging and EMG recording, and to determine the ability of neuromuscular biomarkers to enhance current clinical phenotyping. This cross-sectional study will acquire sonographic images and EMG recordings from the pelvic floor in a cohort of 20 patients with CP/CPPS and 20 controls. Analysis of multiple innovative sonographic techniques (i.e. 2D and 3D, spectral analysis, and elastography) and EMG recordings will identify important biomarkers of CP/CPPS. When combined with current clinical subjective measures, these biomarkers will lead to the development of a new methodology for use in screening CP/CPPS patients. Future studies will utilize the outcomes of this project to enhance the effectiveness of physical therapy for CP/CPPS through clinical implementation of sonographic/EMG screening and the evaluation of treatment outcomes based on sonography/EMG measures. This work is funded by a pilot grant from the USC Southern California Clinical and Translational Science Institute.For more information, contact: Jason Kutch, PhDAssistant Professor(323) firstname.lastname@example.org
This study is about the pelvic floor and urologic chronic pelvic pain syndromes (UCPPS). We hope to learn how the brain controls pelvic floor muscles and other associated muscles in healthy adults, and in adults with diagnosed UCPPS, by using repetitive transcranial magnetic stimulation and electromyography.
Transcranial magnetic stimulation (TMS) is the non-invasive stimulation of the brain by a magnetic coil on the surface of the head. Repetitive transcranial magnetic stimulation (rTMS) involves repetitive TMS stimulations. Electromyography (EMG) uses special metallic sensors on the surface of the skin to detect electrical activity that muscles generate.
You may be eligible to participate if you are:
If enrolled in the study, you will be paid $50 for your time in completion of this study.
For more information, contact: Moheb S. Yani, MAshawkyya@usc.eduHS protocol # HS-14-00479-AM001
1540 Alcazar Street, CHP 155Los Angeles, CA 90089-9006
Phone: (323) 442-2900 Fax: (323) 442-1515