The purpose of this proposal is to determine whether community-based exercise is a feasible and applicable method to improve components of metabolic syndrome (a group of risk factors that occur together and increase the risk for coronary artery disease, stroke, and type 2 diabetes) in breast cancer survivors. It is our hypothesis that community-based group exercise will be feasible and improve body composition, waist circumference, blood pressure, serum levels of insulin, glucose, lipids, C-reactive protein, HbA1c and physical fitness. This is a randomized, controlled 16-week exercise intervention in breast cancer survivors after completion of cancer treatment. The control group will refrain from increasing physical activity levels. The exercise group will participate in thrice weekly 60-minute combined (resistance and aerobic) exercise sessions. All participants will undergo the following outcome measure tests at baseline and upon study completion: blood tests, blood pressure, body composition, muscle strength, cardiorespiratory fitness, and diet logs. All participants will complete physical activity logs during the 16-week period. All participants will have the option of having a biopsy of fat tissue done at baseline and upon study completion for research testing. At the end of the 16-week intervention, the control group will be given the option to participate in the 16-week exercise program. The exercise group will have a follow-up visit with outcome measure tests 12 weeks after completion of the 16-week intervention. Group differences will be compared using ANOVA.
For more information, contact:Christina Dieli-Conwright, PhDPrincipal Investigator(323) firstname.lastname@example.org
The Clinical Exercise Research Center is conducting a study about improving the health and strength in men being treated for prostate cancer. We hope to learn about how resistance exercise and protein supplementation can change muscle mass, strength and quality of life in prostate cancer survivors.
You may be eligible to participate if you:
If enrolled in the study, you will receive 12 weeks of personal training on resistance exercise and body composition testing. If you are randomized to the protein supplementation group, you will also receive a daily supplement of protein powder for 12 weeks.For more information, contact:Jackie Kiwata, MS(323) email@example.comHS Protocol #: HS-13-00315
Principal InvestigatorE. Todd Schroeder, PhDeschroed@usc.edu
1540 Alcazar Street, CHP 155Los Angeles, CA 90089-9006
Phone: (323) 442-2900 Fax: (323) 442-1515