Cystic Fibrosis

  • Yoga as an Intervention for Postural and Neuromuscular Dysfunction in Cystic Fibrosis

    The project is based on the rationale that little information exists about the treatment of neuromuscular dysfunction caused by musculoskeletal deformities in people with cystic fibrosis (CF). Now that the CF population is living longer—the median lifespan is projected to approach the fifties in the next 10 years—there is a need for research dealing with the biomechanical and orthopedic deformities that occur as the disease progresses.

    The Phase I feasibility study will examine the appropriateness of using yoga as therapy for people with CF to treat abnormal posture and the resulting neuromuscular impairments. Dr. George J. Salem, associate professor in the Division of Biokinesiology and Physical Therapy and Dr. Scott Russell, instructor of clinical physical therapy, will develop a yoga program specifically for people with CF and evaluate it in a 10-week trial. Participants will be recruited from the USC Cystic Fibrosis Clinic, which has more than 180 patients.

    Sponsor: USC James H. Zumberge Faculty Research Innovation Fund

    Yoga for Persons with Cystic Fibrosis

    This study will examine the effects of a specifically-tailored yoga program for persons with cystic fibrosis (CF), on overall physical function. This includes pulmonary functional capacity, physical performance, strength, posture, mobility, and self-reported quality of life measures. Safety and adherence of the yoga program will also be evaluated. Participants will be randomized into either a yoga group, receiving classes twice weekly for 8-weeks, or a control group that will not receive yoga. Measurements of function and health will be taken at baseline (mid-May, 2013), after 8 weeks, and again after 6 months. Measurements will take approximately 2 hours at each time point. 

    You may be eligible if you:

    • Have been diagnosed with CF
    • Are between the ages of 18-64
    • Have an FEV >30%
    • Are not currently practicing yoga

     If you agree to participate, you will have the following tests at baseline (Mid-May, 2013), and after 8-weeks and 6 months:

    • Lung function
    • Aerobic capacity
    • Chest circumference
    • Scapular posture
    • Spine curvature
    • Muscle strength and endurance
    • Balance
    • Mood, depression, and anxiety

    For more information, contact:
    Quintilia Avila
    Study Coordinator
    323-442-5570
    qavila@usc.edu