Clinical Research

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  • A clinical trial is a research study involving human volunteers and is designed to answer specific health-related questions. Through clinical trials, or clinical research, investigators are able to find new and improved medicines or treatments for people. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings.

    The NIH definition of a clinical trial which has been adopted by USC's Institutional Review Board is the following: a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes.

  • Ongoing Studies

    Anterior Cruciate Ligament (ACL)
    • Predictors of Recovery Following Anterior Cruciate Ligament Reconstruction

    Cancer
    • Exercise & Prostate Cancer
    • Metabolic Syndrome & Breast Cancer

    Dexterity over a Lifespan
    • Quantification of Dexterous Manipulation
    • Upper/Lower Extremity Control

    Infant and Child Development
    • The Emergence of Movement Dynamics in Selective Infant Leg Action
    • Kick Start: Learning to Move the World
    • Modeling the Infant Exploratory Process 
    • Upper Extremity Strength and Dexterity in Children
    • Using Movement to Measure Early Brain Development

    Healthy Aging 
    • Characterization of Golf Participation
    • Golf Intervention for Veterans Exercise (GIVE) Study

    Low Back Pain
    • Neuromotor Control of Posture in Persons with Low Back Pain

    Mindfulness and Rehabilitation
    • Physical Rehabilitation of Older Adults with Mindfulness (PROAM) Study 

    Neuromuscular Control
    • Brain Control of Hand
    • Control of Hand Muscles
    • Dynamic Control of Muscles
    • Multi-finger Control Strategies
    • Measuring Natural Movement 

     Osteoporosis
    • Bone, Endocrine, Lifestyle Longitudinal Study (BELLS)

    Parkinson's Disease
    • Dexterity in Neuropathologies

    Pelvic Pain
    • Cortical Control of the Pelvic Floor Muscles in Healthy Adults: A Repetitive Transcranial Magnetic Stimulation (rTMS) Study
    • Sonographic Imaging and Electromyography 

    Rotator Cuff Tears
    • Rehabilitation of Patients with Full-thickness Rotator Cuff Tears: Planning and Pilot Study for Feasibility and Efficacy

    Stroke
    • Dose Optimization for Stroke Rehabilitation(DOSE)
    • Neural Mechanisms of Learning

    Tendon Pain
    • Achilles Tendinosis Project
    • Posterior Tibial Tendon Dysfunction (PTTD) project

     

  • Completed Studies

    Aging with Disabilities 
    • Rehabilitation Engineering Research Center (RERC)

    Anterior Cruciate Ligament (ACL)
    • Assessing Movement in Individuals Following Anterior Cruciate Ligament Reconstruction
    • Testosterone and Anterior Cruciate Ligament (TACL)

    Barefoot Running
    • Quantitative analysis of a transition to barefoot running

    Cerebral Palsy
    • Child Habilitation and Motor Performance Skills (CHAMPS)
    • Pediatric Endurance Development and Limb Strengthening (PEDALS)

    Cystic Fibrosis
    • Yoga as an Intervention for Postural and Neuromuscular Dysfunction in Cystic Fibrosis
    • Yoga for Persons with Cystic Fibrosis

    Estrogen and Muscle
    • Influence of Estrogen on Skeletal Muscle Catabolism and Inflammation in Young Women

    Healthy Aging
    • Yoga Empowers Seniors Study (YESS)

    Infant and Child Development 
    • Early Intervention for Infants with Brachial Plexus Injury 

    Low Back Pain
    • Muscle-Specific Strengthening Effectiveness Post Lumbar Microdiscectomy (MUSSEL)
    • Trunk Coordination in Low Back Pain

    Parkinson's Disease
    • Parkinson's Recovery of Brain with Exercise (PROBE)

    Pelvic Pain
    • Functional Magnetic Resonance Imaging

    Spinal Cord Injury and Shoulder Pain
    • Strengthening and Optimal Movement for Painful Shoulders in Chronic Spinal Cord Injury (STOMPS)

    Stoke
    • BION Treatment of Neuromuscular Dysfunction
    • Brain and Behavior Correlates of Arm Rehabilitation (BCAR)
    • Constraint-Induced Therapy and Virtual Scenarios
    • Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (ICARE) Study
    • Interdisciplinary Study of Neuroplasticity and Stroke Rehabilitation (ISNSR)
    • Locomotor Experience Applied Post-Stroke (LEAPS)
    • Northstar Everest
    • Socially Assistive Robots for Post Stroke Rehabilitation